Recent advances in viral inner ear disorders

被引:14
|
作者
Beyea, Jason A.
Agrawal, Sumit K. [2 ]
Parnes, Lorne S. [1 ,3 ]
机构
[1] Univ Western Ontario, Dept Otolaryngol Head & Neck Surg, Schulich Sch Med & Dent, London Hlth Sci Ctr,Univ Hosp, London, ON N6A 5A5, Canada
[2] Univ Western Ontario, Schulich Sch Med & Dent, Dept Elect & Comp Engn, London, ON N6A 5A5, Canada
[3] Univ Western Ontario, Schulich Sch Med & Dent, Dept Clin Neurol Sci, London, ON N6A 5A5, Canada
关键词
congenital hearing loss; Meniere's disease; sudden sensorineural hearing loss; vestibular neuritis; viral labyrinthitis; SENSORINEURAL HEARING-LOSS; ACUTE VESTIBULAR NEURITIS; MENIERES-DISEASE; CYTOMEGALOVIRUS-INFECTION; INCREASED RISK; CHILDREN; THERAPY;
D O I
10.1097/MOO.0b013e328357a6b3
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Purpose of review To highlight the recent advances in the understanding of the diagnosis and management of viral inner ear disorders. Congenital sensorineural hearing loss (cSNHL), sudden sensorineural hearing loss (SSNHL), Meniere's disease, and vestibular neuritis/viral labyrinthitis are discussed. Recent findings Cytomegalovirus infection during pregnancy is an under-recognized cause of hearing loss and central nervous system disease amongst the general population. Prevention of maternal infection and treatment of affected newborns with ganciclovir are promising interventions. Recent evidence in SSNHL patients has resulted in recommendations against viral serology or the use of antivirals. There appears to be an increased risk of SSNHL in patients with comorbid hypertension and diabetes. The viral hypothesis of Meniere's disease remains unproven. In patients with an acute episode of vestibular neuritis, there is presently not sufficient evidence to support the routine use of corticosteroids or antiviral medications. Summary cSNHL remains the most clearly defined of the viral inner ear disorders. The evidence for viral involvement in SSNHL, Meniere's disease, and vestibular neuritis is indirect and equivocal. This review highlights the recent advancements in the diagnosis and management of these disorders.
引用
收藏
页码:404 / 408
页数:5
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