The role of agglutination in bacterial infection

The process of concentration of microorganisms, which leads to inhibition of their growth and death, is a mechanism of nonspecific resistance and immunity in bacterial infection. It was suggested that inhibition and death of microorganisms are caused by deficiency of essential substances in the concentration site, which determines the significance of agglutination in the immunity. Agglutination of microbial bodies increases their concentration in tissues. By contrast, dispersion of bacteria in the tissues weakens the effect of the concentration factor and, consequently, increases the virulence of the bacteria.