Neural mechanisms supporting maladaptive food choices in anorexia nervosa

被引：129

作者：

Foerde, Karin ^{[1
,2
]}

Steinglass, Joanna E. ^{[2
,3
]}

Shohamy, Daphna ^{[4
,5
]}

Walsh, B. Timothy ^{[2
,3
]}

机构：

[1] NYU, Dept Psychol, New York, NY 10003 USA

[2] New York State Psychiat Inst & Hosp, Div Clin Therapeut, New York, NY 10032 USA

[3] Columbia Univ, Dept Psychiat, Med Ctr, New York, NY USA

[4] Columbia Univ, Dept Psychol, Zuckerman Mind Brain Behav Inst, New York, NY 10027 USA

[5] Columbia Univ, Kavli Inst Brain Sci, New York, NY USA

来源：

NATURE NEUROSCIENCE | 2015年 / 18卷 / 11期

关键词：

EATING BEHAVIOR; BRAIN; WOMEN; DISORDERS; BULIMIA; TASTE;

D O I：

10.1038/nn.4136

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

People routinely make poor choices, despite knowledge of negative consequences. We found that individuals with anorexia nervosa, who make maladaptive food choices to the point of starvation, engaged the dorsal striatum more than healthy controls when making choices about what to eat, and that activity in fronto-striatal circuits was correlated with their actual food consumption in a meal the next day.

引用

页码：1571 / 1573

页数：3

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