One-pot synthesis of benzoquinoline and coumarin derivatives using Meldrum's acid in three-component reactions

被引:12
|
作者
Wang, Xue-Mei [1 ]
Ye, He-Lin [2 ]
Qaun, Zheng-Jun [2 ]
Wang, Xi-Cun [2 ]
机构
[1] Lanzhou Univ Technol, Sch Mech & Elect Engn, Lanzhou 730050, Gansu, Peoples R China
[2] Northwest Normal Univ, Key Lab Ecoenvironm Related Polymer Mat, Gansu Key Lab Polymer Mat, Minist Educ,Coll Chem & Chem Engn, Lanzhou 730070, Gansu, Peoples R China
关键词
One-pot synthesis; Meldrum's acid; Multicomponent reaction; Synthesis; Benzo[f]quinoline derivatives; Hexahydrocoumarin derivatives; MULTICOMPONENT REACTIONS; CYCLOADDITION REACTIONS; EFFICIENT SYNTHESIS; CONDENSATION; COMPOUND; PEG-400; ANALOGS; ALDOL;
D O I
10.1007/s11164-012-0762-z
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of 1-aryl-1,2-dihydrobenzo[f]quinolin-3(4H)-one derivatives and 4-aryl-7,7-dimethyl-5-oxo-3,4,5,6,7,8-hexahydrocoumarin derivatives have been synthesized by one-pot multicomponent reaction of Meldrum's acid with benzaldehyde, naphthalene-2-amine, or cyclohexanedione in PEG-400. The method has the advantages of mild reaction conditions, good yields, and easy processing, and is environmentally benign.
引用
收藏
页码:2357 / 2367
页数:11
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