Body size and weight change over adulthood and risk of breast cancer by menopausal and hormone receptor status: a pooled analysis of 20 prospective cohort studies

被引：32

作者：

van den Brandt, Piet A. ^{[1
,2
]}

Ziegler, Regina G. ^{[3
]}

Wang, Molin ^{[4
,5
,6
]}

Hou, Tao ^{[7
]}

Li, Ruifeng ^{[7
]}

Adami, Hans-Olov ^{[8
,9
]}

Agnoli, Claudia ^{[10
]}

Bernstein, Leslie ^{[11
]}

Buring, Julie E. ^{[4
,12
]}

Chen, Yu ^{[13
,14
]}

Connor, Avonne E. ^{[15
]}

Eliassen, A. Heather ^{[4
,6
]}

Genkinger, Jeanine M. ^{[16
,17
]}

Gierach, Gretchen ^{[3
]}

Giles, Graham G. ^{[18
,19
,20
,21
]}

Goodman, Gary G. ^{[22
]}

Hakansson, Niclas ^{[23
]}

Krogh, Vittorio ^{[10
]}

Le Marchand, Loic ^{[24
]}

Lee, I-Min ^{[4
,12
]}

Liao, Linda M. ^{[3
]}

Martinez, M. Elena ^{[25
,26
]}

Miller, Anthony B. ^{[27
]}

Milne, Roger L. ^{[18
,19
,20
,21
]}

Neuhouser, Marian L. ^{[22
]}

Patel, Alpa V. ^{[28
]}

Prizment, Anna ^{[29
,30
]}

Robien, Kim ^{[31
]}

Rohan, Thomas E. ^{[32
]}

Sawada, Norie ^{[33
]}

Schouten, Leo J. ^{[1
]}

Sinha, Rashmi ^{[3
]}

Stolzenberg-Solomon, Rachael Z. ^{[3
]}

Teras, Lauren R. ^{[28
]}

Tsugane, Shoichiro ^{[33
]}

Visvanathan, Kala ^{[15
]}

Weiderpass, Elisabete ^{[34
]}

White, Kami K. ^{[24
]}

Willett, Walter C. ^{[4
,6
,7
]}

Wolk, Alicja ^{[23
,35
]}

Zeleniuch-Jacquotte, Anne ^{[13
,14
]}

Smith-Warner, Stephanie A. ^{[4
,7
]}

机构：

[1] Maastricht Univ, GROW Sch Oncol & Dev Biol, Dept Epidemiol, POB 616, NL-6200 MD Maastricht, Netherlands

[2] Maastricht Univ, Care & Publ Hlth Inst CAPHRI, Dept Epidemiol, POB 616, NL-6200 MD Maastricht, Netherlands

[3] NCI, Div Canc Epidemiol & Genet, NIH, Bethesda, MD 20892 USA

[4] Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA

[5] Harvard TH Chan Sch Publ Hlth, Dept Biostat, Boston, MA USA

[6] Harvard Med Sch, Dept Med, Channing Div Network Med, Boston, MA 02115 USA

[7] Harvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA USA

[8] Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden

[9] Univ Oslo, Inst Hlth, Clin Effectiveness Grp, Oslo, Norway

[10] Fdn Ist Nazl Tumori, Dept Res, Epidemiol & Prevent Unit, I-20133 Milan, Italy

[11] City Hope Natl Med Ctr, Beckman Res Inst, Dept Populat Sci, Duarte, CA USA

[12] Harvard Med Sch, Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02115 USA

[13] NYU, Sch Med, Div Epidemiol, Dept Populat Hlth, New York, NY USA

[14] NYU, Sch Med, Dept Environm Med, New York, NY USA

[15] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA

[16] Columbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, New York, NY USA

[17] Columbia Univ, Irving Med Ctr, Herbert Irving Comprehens Canc Ctr, New York, NY USA

[18] Canc Council Victoria, Canc Epidemiol Div, Melbourne, Vic, Australia

[19] Univ Melbourne, Ctr Epidemiol & Biostat, Melbourne Sch Populat & Global Hlth, Melbourne, Vic, Australia

[20] Monash Univ, Precis Med, Sch Clin Sci, Clayton, Vic, Australia

[21] Monash Univ, Monash Hlth, Clayton, Vic, Australia

[22] Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, 1124 Columbia St, Seattle, WA 98104 USA

[23] Karolinska Inst, Inst Environm Med, Unit Cardiovasc & Nutr Epidemiol, Stockholm, Sweden

[24] Univ Hawaii, Ctr Canc, Canc Epidemiol Program, Honolulu, HI 96822 USA

[25] Univ Calif San Diego, Sch Med, Dept Family Med & Publ Hlth, La Jolla, CA 92093 USA

[26] Univ Calif San Diego, Moores Canc Ctr, La Jolla, CA 92093 USA

[27] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada

[28] Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30329 USA

[29] Univ Minnesota, Sch Med, Div Hematol Oncol & Transplantat, Minneapolis, MN 55455 USA

[30] Univ Minnesota, Sch Publ Hlth, Div Epidemiol & Community Hlth, Minneapolis, MN USA

[31] George Washington Univ, Sch Publ Hlth, Milken Inst, Dept Exercise & Nutr Sci, Washington, DC USA

[32] Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10467 USA

[33] Natl Canc Ctr, Epidemiol & Prevent Grp, Res Ctr Canc Prevent & Screening, Tokyo, Japan

[34] WHO, Int Agcy Res Canc, Lyon, France

[35] Uppsala Univ, Dept Surg Sci, Uppsala, Sweden

来源：

EUROPEAN JOURNAL OF EPIDEMIOLOGY | 2021年 / 36卷 / 01期

基金：

美国国家卫生研究院;

关键词：

Breast neoplasms; Body height; Body weight; Weight change; Estrogen receptor; Cohort studies; MASS INDEX; POSTMENOPAUSAL WOMEN; REGRESSION-MODELS; PHYSICAL-ACTIVITY; SEX-HORMONES; EARLY-LIFE; ESTROGEN; PROGESTERONE; GROWTH; METAANALYSIS;

D O I：

10.1007/s10654-020-00688-3

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Associations between anthropometric factors and breast cancer (BC) risk have varied inconsistently by estrogen and/or progesterone receptor (ER/PR) status. Associations between prediagnostic anthropometric factors and risk of premenopausal and postmenopausal BC overall and ER/PR status subtypes were investigated in a pooled analysis of 20 prospective cohorts, including 36,297 BC cases among 1,061,915 women, using multivariable Cox regression analyses, controlling for reproductive factors, diet and other risk factors. We estimated dose-response relationships and tested for nonlinear associations using restricted cubic splines. Height showed positive, linear associations for premenopausal and postmenopausal BC risk (6-7% RR increase per 5 cm increment), with stronger associations for receptor-positive subtypes. Body mass index (BMI) at cohort baseline was strongly inversely associated with premenopausal BC risk, and strongly positively-and nonlinearly-associated with postmenopausal BC (especially among women who never used hormone replacement therapy). This was primarily observed for receptor-positive subtypes. Early adult BMI (at 18-20 years) showed inverse, linear associations for premenopausal and postmenopausal BC risk (21% and 11% RR decrease per 5 kg/m(2), respectively) with stronger associations for receptor-negative subtypes. Adult weight gain since 18-20 years was positively associated with postmenopausal BC risk, stronger for receptor-positive subtypes, and among women who were leaner in early adulthood. Women heavier in early adulthood generally had reduced premenopausal BC risk, independent of later weight gain. Positive associations between height, baseline (adult) BMI, adult weight gain and postmenopausal BC risk were substantially stronger for hormone receptor-positive versus negative subtypes. Premenopausal BC risk was positively associated with height, but inversely with baseline BMI and weight gain (mostly in receptor-positive subtypes). Inverse associations with early adult BMI seemed stronger in receptor-negative subtypes of premenopausal and postmenopausal BC.

引用

页码：37 / 55

页数：19

共 50 条

[1] Body size and weight change over adulthood and risk of breast cancer by menopausal and hormone receptor status: a pooled analysis of 20 prospective cohort studies
Piet A. van den Brandt
Regina G. Ziegler
Molin Wang
Tao Hou
Ruifeng Li
Hans-Olov Adami
Claudia Agnoli
Leslie Bernstein
Julie E. Buring
Yu Chen
Avonne E. Connor
A. Heather Eliassen
Jeanine M. Genkinger
Gretchen Gierach
Graham G. Giles
Gary G. Goodman
Niclas Håkansson
Vittorio Krogh
Loic Le Marchand
I-Min Lee
Linda M. Liao
M. Elena Martinez
Anthony B. Miller
Roger L. Milne
Marian L. Neuhouser
Alpa V. Patel
Anna Prizment
Kim Robien
Thomas E. Rohan
Norie Sawada
Leo J. Schouten
Rashmi Sinha
Rachael Z. Stolzenberg-Solomon
Lauren R. Teras
Shoichiro Tsugane
Kala Visvanathan
Elisabete Weiderpass
Kami K. White
Walter C. Willett
Alicja Wolk
Anne Zeleniuch-Jacquotte
Stephanie A. Smith-Warner
[J]. European Journal of Epidemiology, 2021, 36 : 37 - 55
[2] Pooled analysis of prospective cohort studies on height, weight, and breast cancer risk
van den Brandt, PA
Spiegelman, D
Yaun, SS
Adami, HO
Beeson, L
Folsom, AR
Fraser, G
Goldbohm, RA
Graham, S
Kushi, L
Marshall, JR
Miller, AB
Rohan, T
Smith-Warner, SA
Speizer, FE
Willett, WC
Wolk, A
Hunter, DJ
[J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 2000, 152 (06) : 514 - 527
[3] Weight loss over 10 years of adulthood and subsequent risk of breast cancer: a pooled analysis of 11 cohort studies
Teras, Lauren R.
Patel, Alpa V.
Wang, Molin
Caan, Bette J.
Chen, Yu
Connor, Avonne E.
Eliassen, A. Heather
Gapstur, Susan M.
Gaudet, Mia M.
Genkinger, Jeanine M.
Giles, Graham G.
Lee, I-Min
Milne, Roger
Sawada, Norie
Sesso, Howard D.
Stampfer, Meir
Tamimi, Rulla
Thomson, Cynthia A.
Tsugane, Shoichiro
Visvanathan, Kala
Zeleniuch-Jacquotte, Anne
Willett, Walter C.
Smith-Warner, Stephanie A.
[J]. CANCER RESEARCH, 2017, 77
[4] A pooled analysis of height, weight and breast cancer risk in seven prospective cohort studies.
vandenBrandt, PA
Hunter, DJ
Spiegelman, D
[J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 1996, 143 (11) : 134 - 134
[5] Body size and breast cancer prognosis in relation to hormone receptor and menopausal status: a meta-analysis
Niraula, Saroj
Ocana, Alberto
Ennis, Marguerite
Goodwin, Pamela J.
[J]. BREAST CANCER RESEARCH AND TREATMENT, 2012, 134 (02) : 769 - 781
[6] Body size and breast cancer prognosis in relation to hormone receptor and menopausal status: a meta-analysis
Saroj Niraula
Alberto Ocana
Marguerite Ennis
Pamela J. Goodwin
[J]. Breast Cancer Research and Treatment, 2012, 134 : 769 - 781
[7] Alcohol consumption and breast cancer risk by estrogen receptor status: in a pooled analysis of 20 studies
Jung, Seungyoun
Wang, Molin
Anderson, Kristin
Baglietto, Laura
Bergkvist, Leif
Bernstein, Leslie
van den Brandt, Piet A.
Brinton, Louise
Buring, Julie E.
Eliassen, A. Heather
Falk, Roni
Gapstur, Susan M.
Giles, Graham G.
Goodman, Gary
Hoffman-Bolton, Judith
Horn-Ross, Pamela L.
Inoue, Manami
Kolonel, Laurence N.
Krogh, Vittorio
Lof, Marie
Maas, Paige
Miller, Anthony B.
Neuhouser, Marian L.
Park, Yikyung
Robien, Kim
Rohan, Thomas E.
Scarmo, Stephanie
Schouten, Leo J.
Sieri, Sabina
Stevens, Victoria L.
Tsugane, Schoichiro
Visvanathan, Kala
Wilkens, Lynne R.
Wolk, Alicja
Weiderpass, Elisabete
Willett, Walter C.
Zeleniuch-Jacquotte, Anne
Zhang, Shumin M.
Zhang, Xuehong
Ziegler, Regina G.
Smith-Warner, Stephanie A.
[J]. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2016, 45 (03) : 916 - 928
[8] Carotenoid intakes and risk of breast cancer defined by estrogen receptor and progesterone receptor status: a pooled analysis of 18 prospective cohort studies
Zhang, Xuehong
Spiegelman, Donna
Baglietto, Laura
Bernstein, Leslie
Boggs, Deborah A.
van den Brandt, Piet A.
Buring, Julie E.
Gapstur, Susan M.
Giles, Graham G.
Giovannucci, Edward
Goodman, Gary
Hankinson, Susan E.
Helzlsouer, Kathy J.
Horn-Ross, Pamela L.
Inoue, Manami
Jung, Seungyoun
Khudyakov, Polyna
Larsson, Susanna C.
Lof, Marie
McCullough, Marjorie L.
Miller, Anthony B.
Neuhouser, Marian L.
Palmer, Julie R.
Park, Yikyung
Robien, Kim
Rohan, Thomas E.
Ross, Julie A.
Schouten, Leo J.
Shikany, James M.
Tsugane, Shoichiro
Visvanathan, Kala
Weiderpass, Elisabete
Wolk, Alicja
Willett, Walter C.
Zhang, Shumin M.
Ziegler, Regina G.
Smith-Warner, Stephanie A.
[J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 2012, 95 (03): : 713 - 725
[9] A Pooled Analysis of Breastfeeding and Breast Cancer Risk by Hormone Receptor Status in Parous Hispanic Women
Sangaramoorthy, Meera
Hines, Lisa M.
Torres-Mejia, Gabriela
Phipps, Amanda, I
Baumgartner, Kathy B.
Wu, Anna H.
Koo, Jocelyn
Ingles, Sue A.
Slattery, Martha L.
John, Esther M.
[J]. EPIDEMIOLOGY, 2019, 30 (03) : 449 - 457
[10] Body size and multiple myeloma mortality: a pooled analysis of 20 prospective studies
Teras, Lauren R.
Kitahara, Cari M.
Birmann, Brenda M.
Hartge, Patricia A.
Wang, Sophia S.
Robien, Kim
Patel, Alpa V.
Adami, Hans-Olov
Weiderpass, Elisabete
Giles, Graham G.
Singh, Pramil N.
Alavanja, Michael
Freeman, Laura E. Beane
Bernstein, Leslie
Buring, Julie E.
Colditz, Graham A.
Fraser, Gary E.
Gapstur, Susan M.
Gaziano, J. Michael
Giovannucci, Edward
Hofmann, Jonathan N.
Linet, Martha S.
Neta, Gila
Park, Yikyung
Peters, Ulrike
Rosenberg, Philip S.
Schairer, Catherine
Sesso, Howard D.
Stampfer, Meir J.
Visvanathan, Kala
White, Emily
Wolk, Alicja
Zeleniuch-Jacquotte, Anne
de Gonzalez, Amy Berrington
Purdue, Mark P.
[J]. BRITISH JOURNAL OF HAEMATOLOGY, 2014, 166 (05) : 667 - 676

← 1 2 3 4 5 →