Nationwide Surveillance of Macrolide-Resistant Mycoplasma pneumoniae Infection in Pediatric Patients

被引：114

作者：

Kawai, Yasuhiro ^{[1
]}

Miyashita, Naoyuki ^{[2
]}

Kubo, Mika ^{[1
]}

Akaike, Hiroto ^{[1
]}

Kato, Atsushi ^{[1
]}

Nishizawa, Yoko ^{[1
]}

Saito, Aki ^{[1
]}

Kondo, Eisuke ^{[1
]}

Teranishi, Hideto ^{[1
]}

Wakabayashi, Tokio ^{[1
]}

Ogita, Satoko ^{[1
]}

Tanaka, Takaaki ^{[1
]}

Kawasaki, Kozo ^{[1
]}

Nakano, Takashi ^{[1
]}

Terada, Kihei ^{[1
]}

Ouchi, Kazunobu ^{[1
]}

机构：

[1] Kawasaki Med Sch, Dept Pediat, Okayama, Japan

[2] Kawasaki Med Sch, Dept Internal Med 1, Okayama, Japan

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2013年 / 57卷 / 08期

关键词：

MOLECULAR ANALYSIS; PULMONARY-DISEASE; STRAINS; INTERLEUKIN-18;

D O I：

10.1128/AAC.00663-13

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We conducted nationwide surveillance to investigate regional differences in macrolide-resistant (MR) Mycoplasma pneumoniae strains in Japan. The prevalence of MR M. pneumoniae in pediatric patients gradually increased between 2008 and 2012. Although regional differences were observed, high levels of MR genes were detected in all seven surveillance areas throughout Japan and ranged in prevalence from 50% to 93%. These regional differences were closely related to the previous administration of macrolides.

引用

页码：4046 / 4049

页数：4

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