Chemotherapy for Advanced Non-Small-Cell Lung Cancer in Elderly Patients

被引：5
|
作者：
Nasser, Fabio [1 ]
Souza Cruz, Marcelo Rocha [2 ]
Riera, Rachel [3 ]
机构：
[1] Hosp Sao Carlos, Med Oncol, Fortaleza, Ceara, Brazil
[2] Beneficencia Portuguesa Sao Paulo, Med Oncol, Sao Paulo, Brazil
[3] Brazilian Cochrane Ctr, Ctr Saude Baseado Evidencia & Avaliacao Tecnol Sa, Sao Paulo, Brazil
来源：
JAMA ONCOLOGY | 2016年 / 2卷 / 12期
关键词：
D O I：
10.1001/jamaoncol.2016.2050
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
CLINICAL QUESTION Do patients above 70 years of age with newly diagnosed advanced non-small-cell lung cancer benefit from platinum-based combination or should they receive non-platinum agents either as single-agent or in combination? BOTTOM LINE For fit elderly patients platinum-based combination is associated with better overall survival, progression-free survival, and objective response rate, however this improvement should be counter balanced against the higher risk of major adverse events (AE).
引用
收藏
页码：1645 / 1646
页数：2
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