Synthesis of Highly Functionalized 9,10-Phenanthrenequinones by Oxidative Coupling Using MoCl5

被引：54

作者：

Trosien, Simon ^{[1
]}

Waldvogel, Siegfried R. ^{[1
]}

机构：

[1] Johannes Gutenberg Univ Mainz, Inst Organ Chem, D-55128 Mainz, Germany

来源：

ORGANIC LETTERS | 2012年 / 14卷 / 12期

关键词：

SCHOLL REACTION; IODINATED BIARYLS; PHENANTHRAQUINONE; DERIVATIVES; EFFICIENT; DEHYDRODIMERIZATION; BULBOPHYLLANTHRONE; INHIBITORS; MECHANISM; OXIDANT;

D O I：

10.1021/ol300948u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The strong oxidative power of molybdenum pentachloride gives rise to an efficient oxidative C-C bond formation of benzil derivatives to the corresponding 9,10-phenanthrenequinones. A highly complementary method to previous approaches was developed. The required derivatives are accessible in a modular fashion and in excellent yields. By this approach the orchid-derived natural product cypripediquinone A was synthesized for the first time.

引用

页码：2976 / 2979

页数：4

共 28 条

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