Oral antibiotic treatment of staphylococcal bone and joint infections in adults

被引：62
|
作者：
Kim, Baek-Nam [1 ]
Kim, Eu Suk [2 ]
Oh, Myoung-Don [3 ]
机构：
[1] Inje Univ, Sanggye Paik Hosp, Dept Internal Med, Seoul, South Korea
[2] Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Songnam, South Korea
[3] Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul 151, South Korea
来源：
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2014年 / 69卷 / 02期
关键词：
antimicrobial treatment; Staphylococcus; osteomyelitis; infectious arthritis; orthopaedic fixation devices; joint prosthesis; FOREIGN-BODY INFECTION; ACUTE HEMATOGENOUS OSTEOMYELITIS; HIGH-DOSE LEVOFLOXACIN; GRAM-POSITIVE BONE; METHICILLIN-RESISTANT; FUSIDIC ACID; IN-VITRO; TRIMETHOPRIM-SULFAMETHOXAZOLE; OSTEOARTICULAR INFECTIONS; CLINDAMYCIN RESISTANCE;
D O I：
10.1093/jac/dkt374
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Bone and joint infections, especially implant-associated infections, are difficult to cure. Long-term antibiotic therapy, combined with appropriate surgery and the removal of prostheses, is required. The most common causative organisms in bone and joint infections are staphylococci. Oral agents are often used after an initial course of parenteral antibiotic treatment. However, it is unclear which oral regimens are most effective in staphylococcal bone and joint infections. We review various oral antibiotic regimens and discuss which regimens are effective for this indication.
引用
收藏
页码：309 / 322
页数：14
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