RETRACTED: UHRF2, another E3 ubiquitin ligase for p53 (Retracted article. See vol. 440, pg. 803, 2013)

被引：4

作者：

Bai, Lu ^{[1
]}

Wang, Xiaohui ^{[1
]}

Jin, Fangmin ^{[1
]}

Yang, Yan ^{[1
]}

Qian, Guanhua ^{[1
]}

Duan, Changzhu ^{[1
,2
]}

机构：

[1] Chongqing Med Univ, Dept Cell Biol & Med Genet, Chongqing 400016, Peoples R China

[2] Chongqing Med Univ, Fac Lab Med, Minist Educ, Key Lab Clin Lab Diagnost, Chongqing 400016, Peoples R China

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2012年 / 425卷 / 04期

基金：

中国国家自然科学基金;

关键词：

UHRF2; p53; Ubiquitin ligase; Cell cycle; Epigenetics; CELL-CYCLE NETWORK; NIRF; DNA; PROTEIN; ARREST; PHASE;

D O I：

10.1016/j.bbrc.2012.08.009

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

UHRF2, ubiquitin-like with PHD and ring finger domains 2, is a nuclear E3 ubiquitin ligase, which is involved in cell cycle and epigenetic regulation. UHRF2 interacts with multiple cell cycle proteins, including cyclins (A2, B1, D1, and El), CDK2, and pRb: moreover. UHRF2 could ubiquitinate cyclin D1 and cyclin El. Also, UHRF2 has been shown to be implicated in epigenetic regulation by associating with DNMTs, G9a, HDAC1, H3K9me2/3 and hemi-methylated DNA. We found that UHRF2 associates with tumor suppressor protein p53, and p53 is ubiquitinated by UHRF2 in vivo and in vitro. Given that both UHRF2 and p53 are involved in cell cycle regulation, this study may suggest a novel signaling pathway on cell proliferation. (C) 2012 Elsevier Inc. All rights reserved.

引用

页码：908 / 911

页数：4

共 50 条

[1] UHRF2, another E3 ubiquitin ligase for p53 (Retraction of vol 425, pg 908, 2012)
Bai, Lu
Wang, Xiaohui
Jin, Fangmin
Yang, Yan
Qian, Guanhua
Duan, Changzhu
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2013, 440 (04) : 803 - 803
[2] RETRACTED: The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis (Retracted article. See vol. 80, pg. 1140, 2020)
Bischof, Oliver
Schwamborn, Klaus
Martin, Nadine
Werner, Andreas
Sustmann, Claudio
Grosschedl, Rudolf
Dejean, Anne
MOLECULAR CELL, 2006, 22 (06) : 783 - 794
[3] RETRACTED: Synthesizing γ-graphyne (Retracted article. See vol. 3, pg. 1312, 2024)
Haley, Michael M.
NATURE SYNTHESIS, 2022, 1 (06): : 413 - 414
[4] RETRACTED: Introduction (Retracted article. See vol. 58, pg. 254, 2020)
Goubier, Frederic
Roques, Magali
VIVARIUM-AN INTERNATIONAL JOURNAL FOR THE PHILOSOPHY AND INTELLECTUAL LIFE OF THE MIDDLE AGES AND RENAISSANCE, 2017, 55 (1-3): : 1 - 8
[5] RETRACTED: Editorial (Retracted article. See vol. 44, pg. 479, 2021)
Bomberg, Mark
JOURNAL OF BUILDING PHYSICS, 2017, 41 (02) : 97 - 100
[6] RETRACTED: E3 Ubiquitin Ligase Fbw7 Negatively Regulates Osteoblast Differentiation by Targeting Runx2 for Degradation (Retracted article. See vol. 294, pg. 68, 2019)
Kumar, Yogesh
Kapoor, Isha
Khan, Kainat
Thacker, Gatha
Khan, Mohd. Parvez
Shukla, Nidhi
Kanaujiya, Jitendra Kumar
Sanyal, Sabyasachi
Chattopadhyay, Naibedya
Trivedi, Arun Kumar
JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 290 (52) : 30975 - 30987
[7] RETRACTED: Did we make a mistake? (Retracted article. See vol. 53, pg. 2105, 2007)
Carlisle, Maxine Alexis
CANADIAN FAMILY PHYSICIAN, 2007, 53 : 1062 - 1063
[8] RETRACTED: DNA barcoding Korean birds (Retracted article. See vol. 35, pg. 357, 2013)
Yoo, Hye Sook
Eah, Jae-Yong
Kim, Jong Soo
Kim, Young-Jun
Min, Mi-Sook
Paek, Woon Kee
Lee, Hang
Kim, Chang-Bae
MOLECULES AND CELLS, 2006, 22 (03) : 323 - 327
[9] RETRACTED: Complex Bogoslovsky Finsler metrics (Retracted article. See vol. 398, pg. 456, 2013)
Peyghan, E.
Tayebi, A.
Ahmadi, A.
JOURNAL OF MATHEMATICAL ANALYSIS AND APPLICATIONS, 2012, 391 (01) : 159 - 169
[10] RETRACTED: Sexuality, intimacy, and gynecological cancer (Retracted article. See vol. 39, pg. 475, 2013)
Schultz, WCMW
Van de Wiel, HBM
JOURNAL OF SEX & MARITAL THERAPY, 2003, 29 (01) : 121 - 128

← 1 2 3 4 5 →