Comparison of two commercially available gamma interferon blood tests for immunodiagnosis of tuberculosis

被引：104

作者：

Dominguez, Jose ^{[1
,3
,4
]}

Ruiz-Manzano, Juan ^{[2
,3
,4
]}

De Souza-Galvao, Malu ^{[3
,5
]}

Latorre, Irene ^{[1
,3
,4
]}

Mila, Celia ^{[5
]}

Blanco, Silvia ^{[1
,3
,4
]}

Angeles Jimenez, M. ^{[5
]}

Prat, Cristina ^{[1
,3
,4
]}

Lacoma, Alicia ^{[1
,3
]}

Altet, Neus ^{[5
]}

Ausina, Vicente ^{[1
,3
,4
]}

机构：

[1] Hosp Univ Germans Trias & Pujol, Fdn Inst Ciencies Salut Germans Trias & Pujol, Microbiol Serv, Barcelona 08916, Spain

[2] Hosp Univ Germans Trias & Pujol, Fdn Inst Ciencies Salut Germans Trias & Pujol, Serv Pneumol, Barcelona 08916, Spain

[3] Univ Autonoma Barcelona, Bellaterra, Spain

[4] Inst Salud Carlos III, Badalona, Spain

[5] Unidad Prevenc & Control TB Barcelona, Barcelona, Spain

来源：

CLINICAL AND VACCINE IMMUNOLOGY | 2008年 / 15卷 / 01期

关键词：

D O I：

10.1128/CVI.00364-07

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We evaluated the T-SPOT. TB and Quantiferon-TB Gold In tube (QFN-G-IT) tests for diagnosing Mycobacterium tuberculosis infection. T-SPOT. TB was more sensitive than QFN-G-IT in diagnosing both active and latent infection. Both gamma interferon tests were unaffected by prior Mycobacterium bovis BCG vaccination. Among children who were not BCG vaccinated but had a positive tuberculin skin test, QFN-G-IT was negative in 53.3% of cases, and T-SPOT. TB was negative in 50% of cases.

引用

页码：168 / 171

页数：4

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