Synthesis of fluoroalkylated alkynes via visible-light photocatalysis

被引：26
|
作者：
Iqbal, Naila [1 ]
Iqbal, Naeem [1 ]
Han, Sung Su [1 ]
Cho, Eun Jin [1 ]
机构：
[1] Chung Ang Univ, Dept Chem, 84 Heukseok Ro, Seoul 06974, South Korea
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2019年 / 17卷 / 07期
基金：
新加坡国家研究基金会;
关键词：
PERFLUOROALKYL IODIDES; CARBOXYLIC-ACIDS; TERMINAL ALKYNES; TRIFLUOROMETHYLATION; FLUORINE; DIFLUOROALKYLATION;
D O I：
10.1039/c8ob02486c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Fluoroalkylated alkynes, which are versatile building blocks for the synthesis of various biologically active organofluorine compounds, were synthesized from easily available alkynyl halides and fluoroalkyl halides by visible-light photocatalysis. Addition of fluoroalkyl radicals to alkynes and subsequent dehalogenation selectively yielded fluoroalkylated alkynes.
引用
收藏
页码：1758 / 1762
页数：5
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