Recent advances in the progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer: A review

被引：6
|
作者：
Shen, Jingjing [1 ]
Wang, Zhongming [2 ]
机构：
[1] Univ Shanghai Sci & Technol, Sch Hlth Sci & Engn, Shanghai, Peoples R China
[2] Univ Shanghai Sci & Technol, Shidong Hosp, Dept Radiat Oncol, Shanghai, Peoples R China
来源：
FRONTIERS IN ONCOLOGY | 2022年 / 12卷
关键词：
gastric cancer; immune checkpoint inhibitors; chemotherapy; targeted therapy; radiotherapy; GASTROESOPHAGEAL JUNCTION CANCER; OPEN-LABEL; SINGLE-ARM; PHASE-II; PLUS PEMBROLIZUMAB; DOUBLE-BLIND; ADENOCARCINOMA; 1ST-LINE; EFFICACY; CHEMOTHERAPY;
D O I：
10.3389/fonc.2022.934249
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Most patients with advanced gastric cancer were treated with palliative therapy, which had a poor curative effect and a short survival time. In recent years, the clinical research of immune checkpoint inhibitors in advanced gastric cancer has made a breakthrough and has become an important treatment for advanced gastric cancer. The modes of immune checkpoint inhibitors in the treatment of advanced gastric cancer include single drug, combined chemotherapy, radiotherapy, and multiple immune drug combination therapy, among which combination therapy shows better clinical efficacy, and a large number of trials are currently exploring more effective combination therapy programs. In this paper, the new clinical research progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer is reviewed, with an emphasis on combination therapy.
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页数：12
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