Vaginal Microbiomes Associated With Aerobic Vaginitis and Bacterial Vaginosis

被引:84
|
作者
Kaambo, Evelyn [1 ,2 ,3 ]
Africa, Charlene [4 ]
Chambuso, Ramadhani [5 ,6 ]
Passmore, Jo-Ann Shelley [1 ,2 ,7 ]
机构
[1] Univ Cape Town, Fac Hlth Sci, Div Med Virol, Dept Pathol,Genital Mucosal HIV & STI Res Grp,Med, Cape Town, South Africa
[2] Univ Cape Town, Div Med Virol, Dept Pathol, Genital Mucosal HIV & STI Res Grp,NRF DST CAPRISA, Cape Town, South Africa
[3] Univ Namibia, Med Sch, Dept Biochem & Med Microbiol, Windhoek, Namibia
[4] Univ Western Cape, MENIS, Med Biosci, Bellville, South Africa
[5] Univ Cape Town, Div Med Virol, Dept Pathol, Cape Town, South Africa
[6] Morogoro Reg Referral Hosp, Dept Gynecol, Morogoro, Tanzania
[7] Natl Hlth Lab Serv, Johannesburg, South Africa
来源
基金
新加坡国家研究基金会;
关键词
aerobic vaginitis; bacterial vaginosis; vaginal microbiomes; group B Streptococcus; preterm birth; GROUP-B STREPTOCOCCUS; LOWER GENITAL-TRACT; PRETERM BIRTH; PREGNANT-WOMEN; INFECTIONS; FLORA; EPIDEMIOLOGY; MANAGEMENT; PROBIOTICS; MORBIDITY;
D O I
10.3389/fpubh.2018.00078
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
A healthy vaginal microbiota is considered to be significant for maintaining vaginal health and preventing infections. However, certain vaginal bacterial commensal species serve an important first line of defense of the body. Any disruption of this microbial barrier might result in a number of urogenital conditions including aerobic vaginitis (AV) and bacterial vaginosis (BV). The health of the vagina is closely associated with inhabitant microbiota. Furthermore, these microbes maintain a low vaginal pH, prevent the acquisition of pathogens, stimulate or moderate the local innate immune system, and further protect against complications during pregnancies. Therefore, this review will focus on vaginal microbial "health" in the lower reproductive tract of women and on the physiological characteristics that determine the well-being of reproductive health. In addition, we explore the distinct versus shared characteristics of BV and AV, which are commonly associated with increased risk for preterm delivery.
引用
收藏
页数:6
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