Concise Total Synthesis of Acortatarin A

被引：15

作者：

Teranishi, Takaaki ^{[1
]}

Kageyama, Masayuki ^{[1
]}

Kuwahara, Shigefumi ^{[1
]}

机构：

[1] Tohoku Univ, Lab Appl Bioorgan Chem, Grad Sch Agr Sci, Aoba Ku, Sendai, Miyagi 9818555, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2013年 / 77卷 / 03期

关键词：

acortatarin; spiro acetal; reactive oxygen species; N-alkylation;

D O I：

10.1271/bbb.120862

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The spirocyclic pyrrole alkaloid, acortatarin A, which had been isolated from a Chinese medicinal plant, was synthesized from a known olefinic compound by a concise six-step sequence involving N-alkylation of a pyrrole derivative with an a-bromo ketone intermediate as the key step.

引用

页码：676 / 678

页数：3

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