Acute haemolytic reaction due to anti-Wb: a case report

被引：1

作者：

Wright, T. ^{[1
]}

Brown, P. ^{[2
]}

Marais, I. ^{[3
]}

Hong, F. S. ^{[1
,4
]}

机构：

[1] Austin Hlth, Austin Pathol, Heidelberg, Vic 3084, Australia

[2] Australian Red Cross Blood Serv, Reference Red Cell Serol, Melbourne, Vic, Australia

[3] Int Blood Grp Reference Lab, Bristol, Avon, England

[4] Australian Red Cross Blood Serv, Transfus Med Serv, Melbourne, Vic, Australia

来源：

VOX SANGUINIS | 2013年 / 105卷 / 04期

关键词：

acute haemolytic transfusion reaction; anti-Wb; Gerbich antigens; Wb antigen; GLYCOPHORIN-C; WEBB WB; ANEMIA; GE;

D O I：

10.1111/vox.12052

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 73-year-old Greek woman presented with symptomatic anaemia requiring red cell transfusion in the setting of progressive chronic lymphocytic leukaemia (CLL). Based on a negative antibody screen, two units of red blood cells (RBCs) were provided for transfusion. During the transfusion, the patient developed an acute haemolytic transfusion reaction (HTR), but recovered with supportive measures. Subsequent antibody investigation confirmed that the patient had an anti-Wb antibody and that the implicated RBC unit was Wb-positive. This is the first report of an anti-Wb causing a clinically significant acute HTR in the literature.

引用

页码：355 / 357

页数：3

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