Pd/Cu catalyzed carbonylation of α-aminoaryl-tethered alkylidenecyclopropanes: synthesis of furoquinoline derivatives

被引：8
|
作者：
Li, Lin [1 ]
Zeng, Hui-Hui [1 ]
Zhang, You-Ya [1 ]
Liang, Jin-Yan [1 ]
Zhang, Xiang-Zhi [1 ]
Peng, Jin-Bao [1 ]
机构：
[1] Wuyi Univ, Sch Biotechnol & Hlth Sci, Jiangmen 529020, Guangdong, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2022年 / 9卷 / 24期
关键词：
QUINOLINE ALKALOIDS; FACILE SYNTHESIS; 3+2 CYCLIZATION; ROOT BARK; CONSTITUENTS; HETEROCYCLES; QUINAZOLINE; METABOLITES; SELECTIVITY; ATMOSPHERE;
D O I：
10.1039/d2qo01420c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A Pd/Cu catalyzed carbonylation of alpha-aminoaryl-tethered ACPs for the synthesis of furoquinoline derivatives has been developed. Oxygen was used as the terminal oxidant in this reaction. A range of furoquinoline derivatives were efficiently prepared in good to excellent yields via the incorporation of a carbonyl group into the product with the cleavage of the proximal C-C bond of the ACPs.
引用
收藏
页码：6802 / 6807
页数：6
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