Quantitative detection of MMP-2 and relationship of the clinical features and prognosis of lung cancer

被引：0
|
作者：
Ma, Jie [1 ]
Peng, Haiyuan [2 ]
Peng, Haiping [1 ]
Zhu, Huifang [1 ]
机构：
[1] Langfang Hlth Vocat Coll, Langfang 065001, Hebei, Peoples R China
[2] Langfang Peoples Hosp, Langfang 065000, Hebei, Peoples R China
来源：
PROCEEDINGS OF THE 2015 INTERNATIONAL CONFERENCE ON SOCIAL SCIENCE AND TECHNOLOGY EDUCATION (ICSSTE 2015) | 2015年 / 18卷
关键词：
lung cancer; MMP-2; gene expression; invasion and metastasis; flow cytometry;
D O I：
暂无
中图分类号：
G40 [教育学];
学科分类号：
040101 ; 120403 ;
摘要：
Objective is to discuss (MMP-2) relationship of matrix metalloproteinase-2 and lung cancer invasion, metastasis and prognosis. Methods: use flow immunoassay for the quantitative detection of MMP-2 expression in 28 cases of benign lung lesions and 78 cases of lung cancer. Results: MMP 2-expression promotes lung cancer is higher than benign lesions (p < 0.05), and there is a significant correlation (p < 0.05) of lung cancer clinical stage and histological grade. Conclusion: The high expression of MMP-2 promotes the invasion and metastasis of lung cancer is, the higher the value is, the higher the clinical stage is, and the lower the tissue differentiation is, suggesting that MMP-2 not only can be used as indicators of lung cancer, but also is effective prognosis.
引用
收藏
页码：183 / 185
页数：3
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