Catheter-related bloodstream infections caused by Gram-negative bacteria

被引:30
|
作者
Bouza, E. [1 ,2 ,3 ,4 ]
Eworo, A. [1 ,2 ,3 ]
Fernandez Cruz, A. [1 ,2 ,3 ]
Reigadas, E. [1 ,2 ,3 ]
Rodriguez-Creixems, M. [1 ,2 ,3 ,4 ]
Munoz, P. [1 ,2 ,3 ,4 ]
机构
[1] Hosp Gen Univ Gregorio Maranon, Clin Microbiol & Infect Dis Dept, Madrid 28007, Spain
[2] Univ Complutense, Fac Med, Dept Med, E-28040 Madrid, Spain
[3] Inst Invest Sanitaria Gregorio Maranon, Madrid, Spain
[4] CIBER Enfermedades Resp CIBERES, Madrid, Spain
关键词
Blood cultures; Catheter-related bloodstream infection; Catheter-related infections; Gram-negative bacteria; Vascular catheter; RISK-FACTORS;
D O I
10.1016/j.jhin.2013.08.008
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
From 2008 to 2010, patients with microbiologically confirmed Gram-negative catheter-related bloodstream infection (GN-CRBSI) were each compared with two randomly selected controls. We included 81 cases (17% of all CRBSI) and 162 controls with CRBSI caused by other pathogens. Incidence of GN-CRBSI was 0.53 episodes per 1000 admissions. Cases were more likely to have underlying neurological disease or gastrointestinal conditions, previous antimicrobial therapy and a shorter time to blood culture positivity. Surgery in the present admission (odds ratio: 3.5), P. aeruginosa (3.6) and a complicated bacteraemia (4.1) were related to a higher mortality rate. GN-CRBSI accounts for 17% of all CRBSI and should be taken into consideration in the empirical therapy of patients with the characteristics mentioned above. (C) 2013 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:316 / 320
页数:5
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