Palladium-Catalyzed Intermolecular Desulfinylative Cross-Coupling of Heteroaromatic Sulfinates

被引：34
|
作者：
Sevigny, Stephane [1 ]
Forgione, Pat [1 ]
机构：
[1] Concordia Univ, Montreal, PQ H4B 1R6, Canada
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2013年 / 19卷 / 07期
基金：
加拿大自然科学与工程研究理事会;
关键词：
C-C bond formation; cross-coupling; heterocycles; palladium; sustainable chemistry; TRANSFER POLYCONDENSATION; ORGANOSILICON POLYMERS; BIARYL SYNTHESIS; ACIDS; ARYLATION; ACTIVATION;
D O I：
10.1002/chem.201204201
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Beauty lies in simplicity: An efficient and environmentally benign palladium-catalyzed protocol has been developed using a sulfinate as a nucleophilic coupling partner. The sulfinate position is arylated chemoselectively in very good yields. The bench-stable, non-hygroscopic heteroaromatic sulfinate salts rapidly undergo cross-coupling without the need of a co-catalyst, base, or additives (see scheme; mw=microwave). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：2256 / 2260
页数：5
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