Treatment of idiopathic restless legs syndrome (RLS) with gabapentin

被引：69
|
作者：
Happe, S
Klösch, G
Saletu, B
Zeitlhofer, J
机构：
[1] Univ Munster, Dept Neurol, D-48129 Munster, Germany
[2] Univ Vienna, Dept Clin Neurol, Vienna, Austria
[3] Univ Vienna, Dept Psychiat, Vienna, Austria
来源：
NEUROLOGY | 2001年 / 57卷 / 09期
关键词：
D O I：
10.1212/WNL.57.9.1717
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Nine patients with idiopathic restless legs syndrome (RLS) were treated with 300 mg of gabapentin as an initial dose and an up-titration until relief of symptoms for 4 weeks. Subjective symptoms improved significantly. Polysomnographic data showed a reduction of periodic leg movements during sleep (PLMS) (p = 0.003) and PLMS index (p = 0.001). The authors conclude that gabapentin provides a well-tolerated and effective treatment of idiopathic RLS.
引用
收藏
页码：1717 / 1719
页数：3
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