IL-10: A potential therapy for allergic inflammation?

被引：140
|
作者：
Pretolani, M [1 ]
Goldman, M [1 ]
机构：
[1] FREE UNIV BRUSSELS,HOP ERASME,DEPT IMMUNOL,B-1070 BRUSSELS,BELGIUM
来源：
IMMUNOLOGY TODAY | 1997年 / 18卷 / 06期
关键词：
D O I：
10.1016/S0167-5699(97)80023-0
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Interleukin 10 (IL-10) is currently regarded as a potential therapy for inflammatory diseases involving T helper 1 (Th1)-type responses because of its ability to downregulate several major functions of Th1 cells and macrophages. Here, evidence is provided that IL-10 could also be useful in controlling Th2-mediated inflammatory processes by preventing the accumulation of activated eosinophils in target tissues.
引用
收藏
页码：277 / 280
页数：4
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