Primate retina imaging with polarization-sensitive optical coherence tomography

被引：52
|
作者：
Ducros, MG [1 ]
Marsack, JD [1 ]
Rylander, HG [1 ]
Thomsen, SL [1 ]
Milner, TE [1 ]
机构：
[1] Univ Texas, Biomed Engn Program, Biomed Engn Laser Lab, Austin, TX 78712 USA
来源：
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION | 2001年 / 18卷 / 12期
关键词：
D O I：
10.1364/JOSAA.18.002945
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
Polarization-sensitive optical coherence tomography (PSOCT) is applied to determine the depth-resolved polarization state of light backreflected from the eye. The birefringence of the retinal nerve fiber layer (RNFL) was observed and measured from PSOCT images recorded postmortem in a Rhesus monkey. An image-processing algorithm was developed to identify birefringent regions in acquired PSOCT retinal images and automatically determine the thickness of the RNFL. Values of the RNFL thickness determined from histology and PSOCT were compared. PSOCT may provide a new method to determine RNFL thickness and birefringence for glaucoma diagnostics. (C) 2001 Optical Society of America
引用
收藏
页码：2945 / 2956
页数：12
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