The Human Connectome Project: A data acquisition perspective

被引：1470

作者：

Van Essen, D. C. ^{[1
]}

Ugurbil, K. ^{[2
]}

Auerbach, E. ^{[2
]}

Barch, D. ^{[3
]}

Behrens, T. E. J. ^{[4
]}

Bucholz, R. ^{[5
]}

Chang, A. ^{[9
,10
]}

Chen, L. ^{[9
,10
]}

Corbetta, M. ^{[6
]}

Curtiss, S. W.

Della Penna, S. ^{[7
,8
]}

Feinberg, D. ^{[9
,10
]}

Glasser, M. F.

Harel, N. ^{[2
]}

Heath, A. C. ^{[11
]}

Larson-Prior, L. ^{[12
]}

Marcus, D. ^{[12
]}

Michalareas, G. ^{[13
]}

Moeller, S. ^{[2
]}

Oostenveld, R. ^{[14
]}

Petersen, S. E. ^{[6
]}

Prior, F. ^{[12
]}

Schlaggar, B. L. ^{[6
]}

Smith, S. M. ^{[4
]}

Snyder, A. Z. ^{[12
]}

Xu, J. ^{[2
]}

Yacoub, E. ^{[2
]}

机构：

[1] Washington Univ, Sch Med, Dept Anat & Neurobiol, St Louis, MO 63110 USA

[2] Univ Minnesota, Ctr Magnet Resonance Res, Minneapolis, MN USA

[3] Washington Univ, Dept Psychol, St Louis, MO 63130 USA

[4] Univ Oxford, Ctr Funct MRI Brain FMRIB, Oxford, England

[5] St Louis Univ, Dept Neurosurg, St Louis, MO 63103 USA

[6] Washington Univ, Dept Neurol, St Louis, MO USA

[7] Univ G DAnnunzio, Dept Neurosci & Imaging, Chieti, Italy

[8] Univ G DAnnunzio, Inst Adv Biomed Technol, Chieti, Italy

[9] Adv MRI Technol, Sebastopol, CA USA

[10] Univ Calif Berkeley, Berkeley, CA 94720 USA

[11] Washington Univ, Dept Psychiat, St Louis, MO USA

[12] Washington Univ, Dept Radiol, St Louis, MO USA

[13] Ernst Strungmann Inst ESI Cooperat, Max Planck Soc, Frankfurt, Germany

[14] Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Nijmegen, Netherlands

来源：

NEUROIMAGE | 2012年 / 62卷 / 04期

关键词：

Connectivity; fMRI; Diffusion imaging; MEG/EEG; Twins; Behavior; CIRCUIT RECONSTRUCTION; BRAIN CONNECTIVITY; NETWORKS; MEG; TRACTOGRAPHY; ARCHITECTURE; SIGNAL; MODEL; FMRI; EEG;

D O I：

10.1016/j.neuroimage.2012.02.018

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The Human Connectome Project (HCP) is an ambitious 5-year effort to characterize brain connectivity and function and their variability in healthy adults. This review summarizes the data acquisition plans being implemented by a consortium of HCP investigators who will study a population of 1200 subjects (twins and their non-twin siblings) using multiple imaging modalities along with extensive behavioral and genetic data. The imaging modalities will include diffusion imaging (dMRI), resting-state fMRI (R-fMRI), task-evoked fMRI (T-fMRI), T1- and T2-weighted MRI for structural and myelin mapping, plus combined magnetoencephalography and electroencephalography (MEG/EEG). Given the importance of obtaining the best possible data quality, we discuss the efforts underway during the first two years of the grant (Phase I) to refine and optimize many aspects of HCP data acquisition, including a new 7T scanner, a customized 31 scanner, and improved MR pulse sequences. (C) 2012 Elsevier Inc. All rights reserved.

引用

页码：2222 / 2231

页数：10

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