Interdisciplinary research: Noradrenergic regulation of adaptive immunity

被引:28
|
作者
Sanders, VM [1 ]
机构
[1] Ohio State Univ, Med Ctr, Dept Mol Virol, Columbus, OH 43210 USA
关键词
psychoneuroimmunology; B cell; T cell; norepinephrine; beta(2)-adrenergic receptor; adrenergic receptor; sympathetic nervous system; antibody; IgG1; cytokines;
D O I
10.1016/j.bbi.2005.07.004
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
To understand the complexity of mechanisms involved in the regulation of adaptive immunity by the sympathetic neurotransmitter norepinephrine and adrenergic receptor stimulation, there must be a rich history of basic science and clinical findings upon which to form hypotheses for testing, as well as a rich supply of individuals trained in two or more disciplines. This review is intended to offer a tour of the past, present, and future discoveries that have been made in the area of adrenergic regulation of adaptive immunity, as well as share a vision of how our field of study will progress years from now, given that every individual who contributes to the interdisciplinary nature of our research is valued. And finally, this review will discuss how the lessons from the past can help us to attain a vision of interdisciplinary research for the future. (c) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码:1 / 8
页数:8
相关论文
共 50 条
  • [1] Adrenergic regulation of adaptive immunity
    Sanders, Virginia M.
    NEURAL AND NEUROENDOCRINE MECHANISMS IN HOST DEFENSE AND AUTOIMMUNITY, 2006, : 81 - 100
  • [2] Adaptive Immunity Regulation and Cerebral Ischemia
    Qin, Xingping
    Akter, Farhana
    Qin, Lingxia
    Cheng, Jing
    Guo, Mei
    Yao, Shun
    Jian, Zhihong
    Liu, Renzhong
    Wu, Songlin
    FRONTIERS IN IMMUNOLOGY, 2020, 11
  • [3] The complement system in regulation of adaptive immunity
    Michael C Carroll
    Nature Immunology, 2004, 5 : 981 - 986
  • [4] IKKα in the regulation of inflammation and adaptive immunity
    Lawrence, T.
    Bebien, M.
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2007, 35 : 270 - 272
  • [5] The complement system in regulation of adaptive immunity
    Carroll, MC
    NATURE IMMUNOLOGY, 2004, 5 (10) : 981 - 986
  • [6] Histamine regulation of innate and adaptive immunity
    Ferstl, Ruth
    Akdis, Cezmi A.
    O'Mahony, Liam
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2012, 17 : 40 - 53
  • [7] Tryptophan catabolism and regulation of adaptive immunity
    Mellor, AL
    Munn, DH
    JOURNAL OF IMMUNOLOGY, 2003, 170 (12): : 5809 - 5813
  • [8] Regulation of innate and adaptive immunity by Notch
    Freddy Radtke
    H. Robson MacDonald
    Fabienne Tacchini-Cottier
    Nature Reviews Immunology, 2013, 13 : 427 - 437
  • [9] Regulation of innate and adaptive immunity by Notch
    Radtke, Freddy
    MacDonald, H. Robson
    Tacchini-Cottier, Fabienne
    NATURE REVIEWS IMMUNOLOGY, 2013, 13 (06) : 427 - 437
  • [10] Mitochondria in the Regulation of Innate and Adaptive Immunity
    Weinberg, Samuel E.
    Sena, Laura A.
    Chandel, Navdeep S.
    IMMUNITY, 2015, 42 (03) : 406 - 417