Building a knowledge base for systems pathology

被引：9

作者：

Michael, Holger ^{[1
]}

Hogan, Jennifer ^{[1
]}

Kel, Alexander ^{[1
]}

Kel-Margoulis, Olga ^{[1
]}

Schacherer, Frank ^{[1
]}

Voss, Nico ^{[1
]}

Wingender, Edgar ^{[1
]}

机构：

[1] Univ Gottingen, Dept Bioinformat, Sch Med, D-37077 Gottingen, Germany

来源：

BRIEFINGS IN BIOINFORMATICS | 2008年 / 9卷 / 06期

关键词：

D O I：

10.1093/bib/bbn038

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Translating the exponentially growing amount of omics data into knowledge usable for a personalized medicine approach poses a formidable challenge. In this articletaking diabetes as a use casewe present strategies for developing data repositories into computer-accessible knowledge sources that can be used for a systemic view on the molecular causes of diseases, thus laying the foundation for systems pathology.

引用

页码：518 / 531

页数：14

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