Novel multiple heterozygous NUDT15 variants cause an azathioprine-induced severe leukopenia in a patient with systemic lupus erythematosus

被引：2

作者：

Otsuka, Mizuna ^{[1
]}

Koga, Tomohiro ^{[1
,2
]}

Sumiyoshi, Remi ^{[1
]}

Furukawa, Kaori ^{[1
]}

Okamoto, Momoko ^{[1
]}

Endo, Yushiro ^{[1
]}

Tsuji, Sosuke ^{[1
]}

Takatani, Ayuko ^{[1
]}

Shimizu, Toshimasa ^{[1
]}

Igawa, Takashi ^{[1
]}

Kawashiri, Shin-ya ^{[1
]}

Iwamoto, Naoki ^{[1
]}

Ichinose, Kunihiro ^{[1
]}

Tamai, Mami ^{[1
]}

Nakamura, Hideki ^{[1
]}

Origuchi, Tomoki ^{[1
]}

Kawakami, Atsushi ^{[1
]}

机构：

[1] Nagasaki Univ, Grad Sch Biomed Sci, Unit Adv Prevent Med Sci, Dept Immunol & Rheumatol, Nagasaki, Japan

[2] Nagasaki Univ, Grad Sch Biomed Sci, Ctr Bioinformat & Mol Med, 1-12-4 Sakamoto, Nagasaki 8528523, Japan

来源：

CLINICAL IMMUNOLOGY | 2019年 / 200卷

关键词：

Systemic lupus erythematosus; Azathioprine; NUDT15; gene; INFLAMMATORY-BOWEL-DISEASE; THIOPURINE; CHILDREN;

D O I：

10.1016/j.clim.2019.02.004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：64 / 65

页数：2

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