Development and utilization of high throughput BCL9/\#946;-catenin binding assays and stabilized \#945;-helical BCL9 peptides to target the BCL9/\#946;-catenin protein-protein interaction as a potential anticancer strategy

被引:0
|
作者
Kawamoto, Steven [1 ]
Thompson, Andrea [1 ]
Coleska, Adriana [1 ]
Wang, Shaomeng [1 ]
机构
[1] Univ Michigan, Ann Arbor, MI 48109 USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
3650
引用
收藏
页数:1
相关论文
共 14 条
  • [1] Design of Triazole-Stapled BCL9 α-Helical Peptides to Target the β-Catenin/B-Cell CLL/lymphoma 9 (BCL9) Protein-Protein Interaction
    Kawamoto, Steven A.
    Coleska, Adriana
    Ran, Xu
    Yi, Han
    Yang, Chao-Yie
    Wang, Shaomeng
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (03) : 1137 - 1146
  • [2] Recent advances in β-catenin/BCL9 protein-protein interaction inhibitors
    Zhang, Hao
    Bao, Ya
    Liu, Chenglong
    Li, Jianqi
    Zhu, Di
    Zhang, Qingwei
    [J]. FUTURE MEDICINAL CHEMISTRY, 2021, 13 (10) : 927 - 940
  • [3] Analysis of the Interaction of BCL9 with β-Catenin and Development of Fluorescence Polarization and Surface Plasmon Resonance Binding Assays for this Interaction
    Kawamoto, Steven A.
    Thompson, Andrea D.
    Coleska, Adriana
    Nikolovska-Coleska, Zaneta
    Yi, Han
    Wang, Shaomeng
    [J]. BIOCHEMISTRY, 2009, 48 (40) : 9534 - 9541
  • [4] New ZW4864 Derivatives as Small-Molecule Inhibitors for the β-Catenin/BCL9 Protein-Protein Interaction
    Wang, Zhen
    Zhang, Min
    Thompson, Harriet M.
    Ji, Haitao
    [J]. ACS MEDICINAL CHEMISTRY LETTERS, 2022, 13 (05): : 865 - 870
  • [5] SOX7 Suppresses Wnt Signaling by Disrupting -Catenin/BCL9 Interaction
    Fan, Rong
    He, HaiYan
    Yao, Wang
    Zhu, YanFeng
    Zhou, XunJie
    Gui, MingTai
    Lu, Jing
    Xi, Hao
    Deng, ZhongLong
    Fan, Min
    [J]. DNA AND CELL BIOLOGY, 2018, 37 (02) : 126 - 132
  • [6] LATS2 Suppresses Oncogenic Wnt Signaling by Disrupting β-Catenin/BCL9 Interaction
    Li, Jiong
    Chen, Xiaohong
    Ding, Xiangming
    Cheng, Yingduan
    Zhao, Bin
    Lai, Zhi-chun
    Al Hezaimi, Khalid
    Hakem, Razqallah
    Guan, Kun-liang
    Wang, Cun-Yu
    [J]. CELL REPORTS, 2013, 5 (06): : 1650 - 1663
  • [7] Use of triazole-stapled BCL9/B9L a-helical peptides to target b-catenin and inhibit Wnt signaling
    Kawamoto, Steven A.
    Coleska, Adriana
    Ran, Xu
    Yi, Han
    Yang, Chao-Yie
    Wang, Shaomeng
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 240
  • [8] Pharmacological inhibition of β-catenin/BCL9 interaction overcomes resistance to immune checkpoint blockades by modulating Treg cells
    Feng, M.
    Jin, J. Q.
    Xia, L.
    Xiao, T.
    Mei, S.
    Wang, X.
    Huang, X.
    Chen, J.
    Liu, M.
    Chen, C.
    Rafi, S.
    Zhu, A. X.
    Feng, Y. -X.
    Zhu, D.
    [J]. SCIENCE ADVANCES, 2019, 5 (05):
  • [9] Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development
    Cantu, Claudio
    Zimmerli, Dario
    Hausmann, George
    Valenta, Tomas
    Moor, Andreas
    Aguet, Michel
    Basler, Konrad
    [J]. GENES & DEVELOPMENT, 2014, 28 (17) : 1879 - 1884
  • [10] Targeted disruption of the BCL9/β-catenin interaction by endosomal-escapable nanoparticles functionalized with an E-cadherin-derived peptide
    Yang, Guang
    Zhang, Jun
    You, Weiming
    Zhao, Xinhan
    Hou, Peng
    He, Wangxiao
    Yan, Jin
    Guo, Hui
    [J]. NANOTECHNOLOGY, 2020, 31 (11)