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Update on Diffuse Alveolar Hemorrhage and Pulmonary Vasculitis
被引:65
|作者:
Krause, Megan L.
Cartin-Ceba, Rodrigo
[1
]
Specks, Ulrich
[1
]
Peikert, Tobias
[1
,2
]
机构:
[1] Mayo Clin, Div Pulm & Crit Care, Dept Internal Med, Rochester, MN 55905 USA
[2] Mayo Clin, Dept Immunol, Rochester, MN 55905 USA
关键词:
Pulmonary vasculitis;
Diffuse alveolar hemorrhage;
ANCA-associated vasculitis;
Granulomatosis with polyangiitis;
Microscopic polyangiitis;
Eosinophilic granulomatosis with polyangiitis;
ANTIBODY-ASSOCIATED VASCULITIS;
ANCA-ASSOCIATED VASCULITIS;
STEM-CELL TRANSPLANT;
DAILY ORAL CYCLOPHOSPHAMIDE;
RECOMBINANT FACTOR VIIA;
SMALL-VESSEL VASCULITIS;
CHURG-STRAUSS-SYNDROME;
OPEN LUNG BIOPSIES;
TERM-FOLLOW-UP;
WEGENERS-GRANULOMATOSIS;
D O I:
10.1016/j.iac.2012.08.001
中图分类号:
R392 [医学免疫学];
学科分类号:
100102 ;
摘要:
Diffuse alveolar hemorrhage is a clinical syndrome that can be a manifestation of multiple different causes. Identification of the underlying etiology is of utmost importance and dictates treatment. Pulmonary vasculitis including antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a common cause of diffuse alveolar hemorrhage. For MV, treatment includes induction followed by maintenance therapy. Rituximab has an increasing role in the treatment of AAV.
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页码:587 / +
页数:15
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