The Strategy, Tactical Approaches and Choice of Combination Therapy in the Treatment of Patients With Arterial Hypertension

This review article presents approaches to the selection of strategy of antihypertensive therapy in hypertensive patients according to the degree of elevation of blood pressure (BP), the level of risk for cardiovascular complications, the doses of drugs used in accordance with current guidelines. A comparative analysis of different strategic approaches is given. The importance of combined antihypertensive therapy, including fixed combinations, not only in terms of reducing BP, improving patient adherence to treatment, but also in terms of a favorable effect on the prognosis is shown. Rational combinations of antihypertensive drugs depending on the specific clinical situation are marked. Attention is paid to the new fixed combinations, including angiotensin converting enzyme inhibitors and calcium antagonists.