Ethnobotanical;
NAPRALERT;
Drug discovery;
Plant;
Ethnomedicine;
NATURAL-PRODUCTS;
ETHNOPHARMACOLOGY;
D O I:
暂无
中图分类号:
R914 [药物化学];
学科分类号:
100701 ;
摘要:
For pharmaceuticals ranging from Digitalis to vincristine, the ethnobotanical approach to drug discovery has proven successful. The value of ethnobotanical information in drug development is based on several factors, which are discussed. Published ethnomedical information has many strengths and weaknesses relative to the ability to establish a corresponding biological effect in the laboratory. The ability to correlate ethnomedical reports with corresponding scientific studies could lead to improved selection of plants for further scientific studies. The application of NAPRALERT database in this regard is also discussed. An elaborate plant to drug pathway has been traced out for young researchers to make the drug discovery pathway more approachable. Various cautions related to possible errors during the ethnobotanical approach have also been highlighted.
机构:
Atal Incubat Ctr CCMB, Ctr Predict Human Model Syst, Hyderabad 500039, IndiaAtal Incubat Ctr CCMB, Ctr Predict Human Model Syst, Hyderabad 500039, India
Parvatam, Surat
Bharadwaj, Sham
论文数: 0引用数: 0
h-index: 0
机构:
Atal Incubat Ctr CCMB, Ctr Predict Human Model Syst, Hyderabad 500039, IndiaAtal Incubat Ctr CCMB, Ctr Predict Human Model Syst, Hyderabad 500039, India
Bharadwaj, Sham
Radha, Vegesna
论文数: 0引用数: 0
h-index: 0
机构:
CSIR Ctr Cellular & Mol Biol, Hyderabad 500007, Andhra Pradesh, IndiaAtal Incubat Ctr CCMB, Ctr Predict Human Model Syst, Hyderabad 500039, India
Radha, Vegesna
Rao, Madhusudhana
论文数: 0引用数: 0
h-index: 0
机构:
Atal Incubat Ctr CCMB, Hyderabad 500039, IndiaAtal Incubat Ctr CCMB, Ctr Predict Human Model Syst, Hyderabad 500039, India