Recent progress of SERS optical nanosensors for miRNA analysis

被引：71
|
作者：
Sun, Yudie [1 ,2 ]
Shi, Lin [1 ]
Mi, Lan [1 ]
Guo, Ruiyan [1 ]
Li, Tao [1 ]
机构：
[1] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China
[2] Anhui Univ Technol, Sch Chem & Chem Engn, Maanshan 243032, Anhui, Peoples R China
来源：
JOURNAL OF MATERIALS CHEMISTRY B | 2020年 / 8卷 / 24期
关键词：
SIGNAL AMPLIFICATION; MICRORNA DETECTION; LIVING CELLS; NUCLEIC-ACIDS; STRATEGY; BIOSENSORS; GOLD; QUANTIFICATION; FLUORESCENCE; CAPTURE;
D O I：
10.1039/d0tb00280a
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
This review focuses on emerging applications of surface-enhanced Raman spectroscopy (SERS) optical nanosensors for miRNA analysis, in which the key enhancement factors of the SERS signal,i.e.SERS-active substrates, SERS nanoprobes and nano-assembly strategy, are emphasized. This article includes many nanomaterials for miRNA analysis by the SERS technique. We summarize these reported nanomaterials mainly according to their function in the miRNA assay biosensor. We also briefly summarize the research progress of these nanomaterials in SERS detection of intracellular miRNA. Finally, we discussed the prospect and limitations of SERS nanosensors for analyzing miRNA.
引用
收藏
页码：5178 / 5183
页数：6
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