Synthesis of some 3-heterylsubstituted indoles

被引：0
|
作者：
Dubey, PK [1 ]
Babu, B [1 ]
机构：
[1] JNTU Coll Engn, Dept Chem, Hyderabad 500072, Andhra Pradesh, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2006年 / 15卷 / 03期
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D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Simple and substituted indoles (1) on Vilsmeier-Haack formylation gave indole-3-aldehydes (2), which on condensation with thiosemicarbazide in refluxing methanol containing acetic acid gave indole-3-thiosemicarbazones (3). Reaction of 3 with alpha-haloketones (4) gave 5. Alternatively, 5 can also be synthesized by the reaction of 3 with acetophenone or acetone in refluxing isopropanol containing catalytic amount of I-2. The structures of all the compounds are based on spectral and analytical data.
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页码：209 / 212
页数：4
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