Synthesis, structure, and cytotoxicity of O-[3-(5-tetrazolyl)propyl]oximes

被引：3
|
作者：
Rubina, K. [1 ]
Abele, E. [1 ]
Belyakov, S. [1 ]
Shestakova, I. [1 ]
Popelis, Yu. [1 ]
机构：
[1] Latvian Inst Organ Chem, LV-1006 Riga, Latvia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 42卷 / 05期
关键词：
D O I：
10.1134/S1070428006050149
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A two-stage method was developed for the conversion of phenyl- and pyridylaldoximes and ketoximes into the corresponding O-[3-(5-tetrazolyl)propyl]oximes. The structure of the sodium salt of 2-acetylpyridine O-[3-(5-tetrazolyl)propyl]oxime was established X-ray diffraction analysis. This compound was shown to possess a high cytotoxic activity in vitro.
引用
收藏
页码：735 / 738
页数：4
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