Heterocyclic scaffolds represent the key structural subunits of many biologically active compounds. Over the last few years iodine-mediated reactions have been extensively studied due to their low cost and eco-friendliness. This Review covers advances in the field of iodine-mediated synthesis of heterocyclic compounds since 2006, especially with an emphasis on mechanisms of ring formation. In this article, syntheses of different heterocycles are classified based on the manipulation of functional groups.
机构:
Shandong Univ, Sch Pharmaceut Sci, Dept Organ Chem, Jinan 250012, Peoples R ChinaShandong Univ, Sch Pharmaceut Sci, Dept Organ Chem, Jinan 250012, Peoples R China
Liu, Zhaopeng
Takeuchi, Yoshio
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Toyama Univ, Lab Bioorgan & Med Chem, Grad Sch Med & Pharmaceut Sci Res, Toyama 9300194, JapanShandong Univ, Sch Pharmaceut Sci, Dept Organ Chem, Jinan 250012, Peoples R China