Characterization of a new monoclonal antibody to human IL-17A

被引：0
|
作者：
Bonnevier, Jody L. [1 ]
Demedeiros, Ricardo [1 ]
Cheng, Qi [1 ]
Coley, Kristen [2 ]
Galitz, David [2 ]
Munshi, Cyrus [2 ]
LaBresh, Kurt [2 ]
Herrera, Julio [2 ]
Ni, Jessie H. T. [1 ]
机构：
[1] R&D Syst Inc, Antibody Applicat, Minneapolis, MN USA
[2] R&D Syst Inc, Mol Biol, Minneapolis, MN USA
来源：
JOURNAL OF IMMUNOLOGY | 2009年 / 182卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
96.14
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Generation and characterization of QLS22001, a humanized monoclonal antibody that neutralizes IL-17A and IL-17F with an extended half-life
    Ma, Huimin
    Zhang, Wei
    Liu, Ke
    Xu, Baoxin
    Li, Minyu
    Meng, Qingyun
    An, Zhenming
    Chen, Bo
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 117
  • [2] IL-17A Monoclonal Antibody Partly Reverses the Glucocorticoids Insensitivity in Mice Exposed to Ozonec
    Xia Fei
    Peng-yu Zhang
    Xue Zhang
    Guo-qing Zhang
    Wu-ping Bao
    Ying-ying Zhang
    Min Zhang
    Xin Zhou
    Inflammation, 2017, 40 : 788 - 797
  • [3] IL-17A Monoclonal Antibody Partly Reverses the Glucocorticoids Insensitivity in Mice Exposed to Ozonec
    Fei, Xia
    Zhang, Peng-yu
    Zhang, Xue
    Zhang, Guo-qing
    Bao, Wu-ping
    Zhang, Ying-ying
    Zhang, Min
    Zhou, Xin
    INFLAMMATION, 2017, 40 (03) : 788 - 797
  • [4] Structure of IL-17A in Complex with a Potent, Fully Human Neutralizing Antibody
    Gerhardt, Stefan
    Abbott, W. Mark
    Hargreaves, David
    Pauptit, Richard A.
    Davies, Rick A.
    Needham, Maurice R. C.
    Langham, Caroline
    Barker, Wendy
    Aziz, Azad
    Snow, Melanie J.
    Dawson, Sarah
    Welsh, Fraser
    Wilkinson, Trevor
    Vaugan, Tris
    Beste, Gerald
    Bishop, Sarah
    Popovic, Bojana
    Rees, Gareth
    Sleeman, Matthew
    Tuske, Steven J.
    Coales, Stephen J.
    Hamuro, Yoshitomo
    Russell, Caroline
    JOURNAL OF MOLECULAR BIOLOGY, 2009, 394 (05) : 905 - 921
  • [5] Humanized monoclonal antibody demonstrating dual inhibition of IL-17A and IL-17F Treatment of psoriasis and psoriatic arthritis
    Crowley, J. J.
    DRUGS OF THE FUTURE, 2018, 43 (07) : 483 - 487
  • [6] First-in-human randomized study of bimekizumab, a humanized monoclonal antibody and selective dual inhibitor of IL-17A and IL-17F, in mild psoriasis
    Glatt, Sophie
    Helmer, Eric
    Haier, Birgit
    Strimenopoulou, Foteini
    Price, Graham
    Vajjah, Pavan
    Harari, Olivier A.
    Lambert, John
    Shaw, Stevan
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2017, 83 (05) : 991 - 1001
  • [7] Monoclonal antibodies targeting IL-17A or its receptor in psoriasis: a new therapeutic approach?
    Bonnet, Marion C.
    Bagot, Martine
    Bensussan, Armand
    M S-MEDECINE SCIENCES, 2012, 28 (12): : 1035 - 1037
  • [8] SECUKINUMAB Fully Human Anti-IL-17 Monoclonal Antibody
    Gonzalez-Gonzalez, L. A.
    Foster, C. S.
    DRUGS OF THE FUTURE, 2011, 36 (06) : 441 - 445
  • [9] Comparison of changes in serum metabolites before and after treatment with IL-17A monoclonal antibody and halomethasone in psoriasis
    Le, Y.
    Zhang, L.
    Chen, L.
    Li, X.
    Yu, Y.
    Zheng, J.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2020, 140 (07) : S119 - S119
  • [10] Generation and characterization of a humanized anti-IL-17A rabbit monoclonal antibody
    Chen, Wei
    Kong, Yong
    Li, Wang
    Zhou, Yi
    Wu, Meijuan
    Chen, Tao
    Wu, Yiliang
    Qiao, Huaiyao
    Qiu, Zhihua
    Qiu, Jiwan
    PROTEIN EXPRESSION AND PURIFICATION, 2021, 187
12345