A new synthesis of novel alkenylated flavones by palladium-catalyzed cross-coupling reactions

被引：12
|
作者：
Fekete, Szabolcs [1 ]
Patonay, Tamas [1 ]
Silva, Artur M. S. [2 ,3 ]
Cavaleiro, Jose A. S. [2 ,3 ]
机构：
[1] Univ Debrecen, Dept Organ Chem, POB 20, H-4010 Debrecen, Hungary
[2] Univ Aveiro, Dept Chem, P-3810193 Aveiro, Portugal
[3] Univ Aveiro, QOPNA, P-3810193 Aveiro, Portugal
来源：
ARKIVOC | 2012年
基金：
匈牙利科学研究基金会;
关键词：
Alkenylation; C-C bond formation; flavone; Heck reaction; Jeffery's conditions; EFFICIENT SYNTHESIS; INHIBITORY-ACTIVITY; DERIVATIVES; CHROMONES; CONSTITUENTS; SCUTELLARIA; ISOFLAVONES; DESIGN; GROWTH; LEAVES;
D O I：
10.3998/ark.5550190.0013.519
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Bromoflavones were treated with various terminal alkynes in palladium-catalyzed cross-coupling reactions under phosphine-free condions to give the expected alkenylated flavones in moderate to good yields. The presence of two different beta hydrogens in the terminal alkene led to the formation of both alkenylated and alkylated products.
引用
收藏
页码：210 / 225
页数：16
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