Mediastinal mature teratoma with spontaneous malignant transformation

被引：7
|
作者：
Abid, H. [1 ]
Neji, H. [1 ]
Haddar, S. [1 ]
Ammar, I. [1 ]
Ayadi, L. [2 ]
Msaad, S. [3 ]
Ben Mahfoudh, K. [1 ]
Mnif, J. [1 ]
机构：
[1] CHU Habib Bourguiba, Serv Imagerie Med, Sfax 3029, Tunisia
[2] CHU Habib Bourguiba, Serv Anatomopathol, Sfax 3029, Tunisia
[3] CHU Hedi Chaker, Serv Pneumol, Sfax, Tunisia
来源：
REVUE DES MALADIES RESPIRATOIRES | 2013年 / 30卷 / 05期
关键词：
Mature teratoma; Mediastinum; Malignant transformation; CYSTIC TERATOMA; ADENOCARCINOMA;
D O I：
10.1016/j.rmr.2012.11.006
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Introduction. - Malignant teratomas can be either immature teratomas or they can develop after treatment of other malignant germ cell tumors with chemotherapy or radiotherapy. Spontaneous malignant transformation of mature teratomas is very rare. Observation. - We report the case of a patient complaining of atypical chest pain. Chest plain radiography showed a right anterior mediastinal mass. Computed tomography revealed a heterogeneous mediastinal mass with fat areas and calcification. There were hilar and mediastinal lymph nodes as well as lung parenchymal nodules. CT-guided and then surgical biopsies confirmed the diagnosis of a mature teratoma, which had degenerated into a digestive adenocarcinoma. Conclusion. - Spontaneous malignant transformation of mature mediastinal teratoma is very rare. The diagnosis of malignant transformation is based on radiological examinations, laboratory tests and histological studies. (C) 2013 Published by Elsevier Masson SAS on behalf of SPLF.
引用
收藏
页码：424 / 428
页数：5
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