Sensitivity analysis for incomplete categorical data

被引:47
|
作者
Kenward, Michael G. [1 ]
Goetghebeur, Els J. T. [2 ]
Molenberghs, Geert [3 ]
机构
[1] Univ London London Sch Hyg & Trop Med, London WC1E 7HT, England
[2] Univ Ghent, Dept Appl Math & Informat Sci, Ghent, Belgium
[3] Limburgs Univ Ctr, Biostat, B-3590 Diepenbeek, Belgium
关键词
contingency table; missing at random; overspecified model; saturated model;
D O I
10.1177/1471082X0100100104
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
Classical inferential procedures induce conclusions from a set of data to a population of interest, accounting for the imprecision resulting from the stochastic component of the model. This is usually done by means of precision or interval estimates. Less attention is devoted to the uncertainty arising from (unplanned) incompleteness in the data, even though the majority of clinical studies suffer from incomplete follow-up. Through the choice of an identifiable model for non-ignorable non-response, one narrows the possible data generating mechanisms to the point where inference only suffers from imprecision. Some proposals have been made for assessment of sensitivity to these modelling assumptions; many are based on fitting several plausible but competing models. We propose a formal approach which identifies and incorporates both sources of uncertainty in inference: imprecision due to finite sampling and ignorance due to incompleteness. The developments focus on contingency tables, and are illustrated using data from a HIV prevalence study and data from a psychiatric study.
引用
收藏
页码:31 / 48
页数:18
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