Macrophage hemoglobin scavenger receptor CD163 is functionally linked to heme oxygenase-1 and ferritin expression in human diabetic atherosclerotic plaques

被引:0
|
作者
Purushothaman, Meerarani [1 ]
Purushothaman, K-Raman [1 ]
Levy, Andrew P. [2 ]
Lento, Patrick A. [1 ]
Fallon, John T. [1 ]
Fuster, Valentin [1 ]
Sharma, Samin K. [1 ]
Moreno, Pedro R. [1 ]
机构
[1] Mt Sinai Sch Med, New York, NY USA
[2] Technion Israel Inst Technol, Haifa, Israel
来源
FASEB JOURNAL | 2010年 / 24卷
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页数:1
相关论文
共 46 条
  • [1] Macrophage Hemoglobin Scavenger Receptor CD163 Is Functionally Linked to Heme-Oxygenase-1 and Ferritin Expression in Human Diabetic Atherosclerotic Plaques
    Purushothaman, Meerarani
    Purushothaman, K-Raman
    Levy, Andrew P.
    Zias, Elias A.
    Lento, Patrick A.
    Fallon, John T.
    Fuster, Valentin
    Moreno, Pedro R.
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 53 (10) : A427 - A427
  • [2] The macrophage hemoglobin scavenger receptor (HbSR/CD163) and hemoglobin catabolism by macrophages contribute to enhanced ferritin expression in human atherosclerotic lesions
    Li, W
    Yuan, XM
    ATHEROSCLEROSIS SUPPLEMENTS, 2003, 4 (02) : 80 - 80
  • [3] Incoordinate down-regulation of heme oxygenase-1 to hemoglobin scavenger receptor (CD163) in peripheral blood mononuclear cells from patients with ESRD
    Nagaba, Y
    Sakamoto, H
    Matsuo, T
    Kishi, Y
    Makino, T
    Aoyama, T
    Kamata, K
    Kobayashi, Y
    Higashihara, M
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2002, 13 : 218A - 218A
  • [4] Macrophage hemoglobin scavenger receptor and ferritin accumulation in human atherosclerotic lesions
    Li, W
    Xu, LH
    Yuan, XM
    SIGNAL TRANSDUCTION PATHWAYS, CHROMATIN STRUCTURE, AND GENE EXPRESSION MECHANISMS AS THERAPEUTIC TARGETS, 2004, 1030 : 196 - 201
  • [5] Atherosclerotic intralesional haemorrhage moulds monocyte differentiation into a macrophage antioxidant phenotype bearing the hemoglobin scavenger receptor CD163
    Boyle, Joseph J.
    Philippidis, Pandelis
    Horncastle, Donna
    Cantilena, Sandra
    Leung, Viola
    Taylor, Kenneth M.
    Landis, Clive
    Haskard, Dorian
    FASEB JOURNAL, 2008, 22
  • [6] Association Between Hemoglobin Scavenger Receptor and Heme Oxygenase-1 Related Anti-Inflammatory Mediators in Human Coronary Plaques
    Matsumi, Hiroaki
    Yunoki, Kei
    Naruko, Takahiko
    Komatsu, Ryushi
    Itoh, Akira
    Haze, Kazuo
    Sugioka, Kenichi
    Matsumura, Yoshiki
    Wada, Satoko
    Inaba, Mayumi
    Iwasa, Yoko
    Yoshiyama, Minoru
    Ueda, Makiko
    CIRCULATION, 2011, 124 (21)
  • [7] The Haptoglobin-CD163-Heme Oxygenase-1 Pathway for Hemoglobin Scavenging
    Thomsen, Jens Haugbolle
    Etzerodt, Anders
    Svendsen, Pia
    Moestrup, Soren K.
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2013, 2013
  • [8] Expression of the macrophage haemoglobin scavenger receptor CD163 is regulated by extracellular iron
    Goulding, N. J.
    Bergin, P. J.
    Pope, A.
    King, H.
    IMMUNOLOGY, 2008, 125 : 7 - 7
  • [9] Down-regulation of heme oxygenase-1 gene expression is associated with decreased ferritin and increased iron deposition in diabetic atherosclerotic plaques
    Purushothaman, Meerarani
    Levy, Andrew P.
    Purushothaman, K-Raman
    Astudillo, Luis
    Lento, Patrick
    Fallon, John T.
    Fuster, Valentin
    Moreno, Pedro R.
    DIABETES, 2008, 57 : A179 - A179
  • [10] The macrophage hemoglobin scavenger receptor (CD163) as a genetically determined disease modifying pathway in atherosclerosis
    Schaer, DJ
    ATHEROSCLEROSIS, 2002, 163 (01) : 199 - 201