A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Efficacy of AMG 827 in Subjects With Moderate to Severe Crohn's Disease

被引：75
|
作者：
Targan, Stephan R.
Feagan, Brian G.
Vermeire, Severine
Panaccione, Remo
Melmed, Gil Y.
Blosch, Consuelo
Newmark, Richard
Zhang, Nan
Chon, Yun
Lin, Shao-Lee
Klekotka, Paul
机构：
来源：
GASTROENTEROLOGY | 2012年 / 143卷 / 03期
关键词：
D O I：
10.1053/j.gastro.2012.07.084
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：E26 / E26
页数：1
相关论文
共 50 条
  • [1] A Randomized, Double-Blind, Placebo-Controlled, Multiple-Dose Study to Evaluate the Safety, Tolerability, and Efficacy of Brodalumab (AMG 827) in Subjects with Moderate to Severe Asthma
    Busse, William W.
    Holgate, Stephen T.
    Kerwin, Edward M.
    Chon, Yun
    Feng, JingYuan
    Lin, Joseph H.
    Lin, Shao-Lee
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2013, 131 (02) : AB230 - AB230
  • [2] A Randomized, Double-Blind, Placebo-Controlled, Multiple-Dose Study to Evaluate the Safety, Tolerability, and Efficacy of Brodalumab (AMG 827) in Subjects with Rheumatoid Arthritis and an Inadequate Response to Methotrexate.
    Pavelka, Karel
    Chon, Yun
    Newmark, Richard
    Erondu, Ngozi
    Lin, Shao-Lee
    [J]. ARTHRITIS AND RHEUMATISM, 2012, 64 (10): : S362 - S362
  • [3] A phase II, Multicentre, Randomised, Double-Blind, Placebo-controlled Study to Evaluate Safety, Tolerability, and Efficacy of Amiselimod in Patients with Moderate to Severe Active Crohn's Disease
    D'Haens, Geert
    Danese, Silvio
    Davies, Martin
    Watanabe, Mamoru
    Hibi, Toshifumi
    [J]. JOURNAL OF CROHNS & COLITIS, 2022, 16 (05): : 746 - 756
  • [4] Safety, tolerability, and efficacy of brodalumab (AMG 827) in subjects with moderate to severe asthma with high bronchodilator reversibility: subgroup analysis of a randomised, double-blind, placebo-controlled, multiple-dose study
    Holgate, S.
    Busse, W. W.
    Kerwin, E.
    Chon, Y.
    Feng, J.
    Lin, J.
    Lin, S-L
    [J]. ALLERGY, 2013, 68 : 41 - 42
  • [5] Onercept for moderate-to-severe Crohn's disease: A randomized, double-blind, placebo-controlled trial
    Rutgeerts, Paul
    Sandborn, William J.
    Fedorak, Richard N.
    Rachmilewitz, Daniel
    Tarabar, Dino
    Gibson, Peter
    Nielsen, Ole Haagen
    Wild, Gary
    Schreiber, Stefan
    Rossi, Claudia Pena
    Zignani, Monia
    [J]. CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2006, 4 (07) : 888 - 893
  • [6] A randomized, double-blind placebo-controlled study of the safety of apadenoson in subjects with moderate to severe Chronic Obstructive Pulmonary Disease (COPD)
    Williams, S. P.
    Colice, G.
    Mcardle, J. R.
    Lankford, A.
    Kajdasz, D. K.
    Reed, C. R.
    [J]. EUROPEAN HEART JOURNAL SUPPLEMENTS, 2011, 13 (0A) : A54 - A54
  • [7] A double-blind, placebo-controlled, randomized study to evaluate the efficacy, safety and tolerability of tegaserod in patients with irritable bowel syndrome
    Nyhlin, H
    Bang, C
    Elsborg, L
    Silvennoinen, J
    Holme, I
    Rüegg, P
    Jones, J
    Wagner, A
    [J]. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2004, 39 (02) : 119 - 126
  • [8] A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Evaluate the Efficacy and Safety of AMG 334 for the Prevention of Episodic Migraine
    Sun, H.
    Silberstein, S.
    Dodick, D. W.
    Reuter, U.
    Ashina, M.
    Saper, J. R.
    Cady, R.
    Chon, Y.
    Dietrich, J.
    Lenz, R.
    [J]. HEADACHE, 2015, 55 : 132 - 132
  • [9] A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study of Brodalumab in Patients With Moderate-to-Severe Crohn's Disease
    Targan, Stephan R.
    Feagan, Brian
    Vermeire, Severine
    Panaccione, Remo
    Melmed, Gil Y.
    Landers, Carol
    Li, Dalin
    Russell, Chris
    Newmark, Richard
    Zhang, Nan
    Chon, Yun
    Hsu, Yi-Hsiang
    Lin, Shao-Lee
    Klekotka, Paul
    [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2016, 111 (11): : 1599 - 1607
  • [10] A randomized, double-blind placebo-controlled study of the safety of apadenoson in subjects with mild or moderate asthma
    Williams, S. P.
    Mcardle, J. R.
    Colice, G.
    Lankford, A.
    Kajdasz, D. K.
    Reed, C. R.
    [J]. EUROPEAN HEART JOURNAL SUPPLEMENTS, 2011, 13 (0A) : A95 - A96
12345