Differential induction of gene expression may explain differences in reported adverse event profiles between the FGFR-inhibitors derazantinib and erdafitinib: An analysis in safety relevant normal tissues from urothelial cancer (UC) patient-derived mouse xenograft (PDX) models

被引:1
|
作者
McSheehy, P. [1 ]
Guo, J. [2 ]
Beebe, K. [2 ]
Eisner, J. R. [2 ]
Anderson, S. [3 ]
Braun, S. [3 ]
Engelhardt, M. [3 ]
Kellenberger, L. [1 ]
Lane, H. [1 ]
Milburn, M. [2 ]
机构
[1] Basilea Pharmaceut Int Ltd, Res, Basel, Switzerland
[2] GeneCentr Therapeut Inc, Res, Durham, NC USA
[3] Basilea Pharmaceut Int Ltd, Dev, Basel, Switzerland
关键词
D O I
10.1016/j.annonc.2020.08.1352
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1960P
引用
收藏
页码:S1103 / S1104
页数:2
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