Therapeutic and Diagnostic Challenges in Myasthenia Gravis

被引:5
|
作者
Thy Nguyen [1 ]
Phan, Cecile L. [2 ]
Supsupin, Emilio, Jr. [3 ]
Sheikh, Kazim [4 ]
机构
[1] Univ Texas Hlth Sci Ctr Houston, Dept Neurol, McGovern Med Sch, 6431 Fannin St,MSE R 462, Houston, TX 77030 USA
[2] 7-125 Clin Sci Bldg, Edmonton, AB T6G 2R7, Canada
[3] Dept Diagnost & Intervent Imaging, 6431 Fannin St 2-103 MSMB, Houston, TX 77030 USA
[4] Univ Texas Hlth Sci Ctr Houston, Dept Neurol, McGovern Med Sch, 6431 Fannin St,MSE R454, Houston, TX 77030 USA
关键词
Neuromuscular junction disorder; Myasthenia gravis; Ptosis; Weakness; CLINICAL CHARACTERISTICS; MUSK; PREGNANCY; RITUXIMAB; EPIDEMIOLOGY; BIRTH; RISK;
D O I
10.1016/j.ncl.2020.03.005
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
“Myasthenia gravis (MG) is the most common autoimmune neuromuscular disorder. This article highlights several cases that the practicing neurologist may encounter in the treatment of MG. Diagnostic uncertainty continues to be an issue in patients who are seronegative to the 2 most common antibodies, acetylcholine receptor and muscle-specific tyrosine kinase (MuSK). Specific populations of patients with MG including MuSK MG, thymomatous MG, refractory MG, and pregnant women also require special consideration. This article reviews specific cases and an update on current management.” © 2020
引用
收藏
页码:577 / 590
页数:14
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