Study of lipoprotein profile in people infected with HIV in Cote d'Ivoire.

Aids is a cachexysing disease which is striking Africa. Cote d'Ivoire with its 12% seroprevalence is paying a heavy tribute to this pandemia. The course of the disease is characterized by the occurrence of immunological and biochemical disorders. The aim of this study is to offer African practitioners, clinicians and biologists some biochimical parameters that would help them to follow up people infected with HIV. The authors determined the lipoprotein profile in 204 people (112 Aids patients, 61 HIV infected asymptomatics and 31 controls seronegative to HIV) of both sexes aged 17 to 70 years old The results show a relatively high level of triglyceridemia, a decreased level of total cholesterol, apo proteins A1 and B and a hypergammaglobulinemia with concomitant and significant increase in the level of orosomucoide as a stigmate of inflammation. These data could help practitioners who lack CD4/CD8 count and viral load monitoring in the follow up of their AIDS patients.