2D NMR study of solution conformations and complete H-1 and C-13 chemical shifts assignments of vitamin D metabolites and analogs

In addition to conventional 1D H-1 and C-13 NMR, including DEFT and NOE methods, 2D-shift-correlated NMR techniques (H-1-H-1 COSY and H-1-C-13 HMQC) were used, providing an approach to the complete signal assignments for vitamin D analogs and model compounds. On the basis of NMR data,solution conformations of vitamin D and analogs were studied.