Synthesis and Asymmetric Oxidation of (Caranylsulfanyl)-1H-imidazoles

被引：6

作者：

Demakova, Marina Y. ^{[1
]}

Sudarikov, Denis V. ^{[1
]}

Rubtsova, Svetlana A. ^{[1
]}

Frolova, Larisa L. ^{[1
]}

Popov, Alexey V. ^{[1
]}

Slepukhin, Pavel A. ^{[2
]}

Kuchin, Alexander V. ^{[1
]}

机构：

[1] RAS, Inst Chem, Komi Sci Ctr, Ural Div, RU-167982 Syktyvkar, Russia

[2] RAS, Inst Organ Synth, Ural Div, RU-620041 Ekaterinburg, Russia

来源：

HELVETICA CHIMICA ACTA | 2012年 / 95卷 / 06期

基金：

俄罗斯基础研究基金会;

关键词：

1H-Imidazoles; (caranylsulfanyl)-; Asymmetric oxidation; X-Ray crystallography; ALCOHOLS; ALKYLATION; SULFOXIDES; ALDEHYDES; SULFIDES; THIOLS;

D O I：

10.1002/hlca.201100484

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

For the first time 2-(cis-caran-4-ylsulfanyl)-1H-imidazole, 1-methyl-2-(cis-caran-4-ylsulfanyl)-1H-imidazole, and 2-(cis-caran-4-ylsulfanyl)-1H-benzimidazole (carane=3,7,7-trimethylbicyclo[4.1.0]heptane) were synthesized, and the asymmetric oxidation of these compounds was also carried out. It was shown that oxidation by the Bolm system and the modified system of Sharpless lead to corresponding sulfoxides with de values of 91100%.

引用

页码：940 / 950

页数：11

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