Fiberoptic SERS sensors using plasmonic nanostar probes for detection of molecular biotargets

被引：0

作者：

Cupil-Garcia, Vanessa ^{[1
,2
]}

Strobbia, Pietro ^{[1
,3
]}

Ran, Yang ^{[1
]}

Crawford, Bridget M. ^{[3
]}

Wang, Hsin-neng ^{[1
,3
]}

Zentella, Rodolfo ^{[4
]}

Sun, Tai-Ping ^{[4
]}

Tuan Vo-Dinh ^{[1
,2
,3
,5
]}

机构：

[1] Duke Univ, Fitzpatrick Inst Photon, Durham, NC 27708 USA

[2] Duke Univ, Dept Chem, Durham, NC 27708 USA

[3] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA

[4] Duke Univ, Dept Biol, Durham, NC 27708 USA

[5] Duke Univ, Duke Canc Inst, Durham, NC 27708 USA

来源：

PLASMONICS IN BIOLOGY AND MEDICINE XVII | 2020年 / 11257卷

基金：

中国国家自然科学基金; 美国国家科学基金会;

关键词：

surface-enhanced Raman scattering; optrode; nanoparticle; plasmonics; GENETICALLY-MODIFIED ORGANISMS;

D O I：

10.1117/12.2552993

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Our group has integrated surface-enhanced Raman scattering (SERS) silver coated gold nanostars on an optical fiber. Fiber-based sensors are an in-situ technology that can simultaneously bring the sensor and light to the sample without disturbing the environment. This technology is a multi-use method that does not require complex sample preparation. Fiber sensors or optrodes, enable the detection of analytes in samples that are difficult to access. Additionally, optrodes allow for specific detection while evading background signals from non-target regions. The fiber-optrode was used to detect miRNA and illegal food additives.

引用

页数：8

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