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Controlling proteolysis of Clp peptidase: a possible target for combating mitochondrial diseases Comment
被引：5
|作者：
da Silva, Ronivaldo Rodrigues
[1
]
机构：
[1] Univ Estadual Paulista Julio de Mesquita Filho UN, Inst Biociencias Letras & Ciencias Exatas, Sao Jose Do Rio Preto, SP, Brazil
来源：
关键词：
Chaperone;
Cellular function;
Protease;
Proteostasis;
PROTEASES;
UPR;
D O I：
10.1016/j.biocel.2019.03.007
中图分类号：
Q5 [生物化学];
Q7 [分子生物学];
学科分类号：
071010 ;
081704 ;
摘要：
Some mechanisms of cellular stress, aging, and apoptosis are related to proteolysis. With respect to ClpP, little is known about the mechanical manner in which the substrate is hydrolyzed in and released from the degradation chamber. Furthermore, what would be the real influence of ClpP in mammalian UPRmt?
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页码：140 / 142
页数：3
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