Life(span) in balance: oxygen fuels a sophisticated neural network for lifespan homeostasis in C-elegans

被引：1
|
作者：
Skora, Susanne [1 ]
Zimmer, Manuel [1 ]
机构：
[1] Res Inst Mol Pathol, A-1030 Vienna, Austria
来源：
EMBO JOURNAL | 2013年 / 32卷 / 11期
关键词：
NEMATODE CAENORHABDITIS-ELEGANS; LONGEVITY; NEURONS;
D O I：
10.1038/emboj.2013.101
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A key finding of modern ageing research is that our limitation in lifespan is more than the result of accumulated organismal decay. Lifespan is regulated by genetically defined chemosensory and endocrine pathways, which integrate signals that reflect the internal and external status of the animal. New findings by Liu and Cai unravel a role for the environmental gases oxygen and carbon dioxide in the regulation of lifespan homeostasis and thus a novel function of oxygen-chemosensory neurons in C. elegans.
引用
收藏
页码：1499 / 1501
页数：3
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