The Kanye axis of Late Archaean/Palaeoproterozoic rifting, volcanism and sedimentation, is postulated mainly from three-dimensional basin modelling of the lower Transvaal Supergroup, carried out using DATAMINE software. Acid lavas and intrusives of the pre-Transvaal Kanye suite, which occur in eastern Botswana adjacent parts of South Africa and further eastwards below the Dennilton fragment in the Bushveld complex, lie on the inferred axis. Both lowermost Transvaal volcano-sedimentary successions and the overlying sheet sandstones of the Black Reef Formation have major axes of subsidence and deposition along this proposed Kanye trend in the DATAMINE basin-fill models. Geophysical data also support the suggested Kanye trend, as does the location of younger intrusive bodies such as the Pilanesberg and Goudini alkaline complexes in South Africa. Three-dimensional basin modelling using DATAMINE software provides a powerful tool in evaluating the tectono-sedimentary history of ancient Precambrian basins, such as that of the Late Archaean/Palaeoproterozoic Transvaal Supergroup of southern Africa.